NTS aired an episode dedicated to the music of The Isley Brothers on 16 July 2021. The Isley Brothers has been played on NTS over 220 times, featured on 196 episodes and was first played on 14 November 2012.

The Isley Brothers are an American musical group originally from Cincinnati, Ohio, that started as a vocal trio consisting of brothers O'Kelly Isley Jr., Rudolph Isley and Ronald Isley in the 1950s. With a career spanning over eight decades, the group has enjoyed one of the "longest, most influential, and most diverse careers in the pantheon of popular music".

Together with a fourth brother, Vernon, the group…